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TNFRSF10A

Gene

TNF receptor superfamily member 10a

HGNCHGNC:11904EnsemblENSG00000104689NCBI Gene8797
Locus: gene with protein productLocation: 8p21.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDR4 · Apo2 · TRAILR-1 · CD261 · TRAILR1
View full nomenclature history (6)
Alias symbolsDR4, Apo2, TRAILR-1, CD261, TRAILR1
Previous namestumor necrosis factor receptor superfamily, member 10a

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Macular Degeneration
Neurodegenerative Diseases
Central Serous Chorioretinopathy
Wet macular degeneration
COVID-19
Endometriosis
Carcinoma, Non-Small-Cell Lung
Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesTumor necrosis factor receptor superfamily

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.