TPR

Gene

translocated promoter region, nuclear basket protein

HGNCHGNC:12017 EnsemblENSG00000047410 NCBI Gene7175

Locus: gene with protein productLocation: 1q31.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

View full nomenclature history (1)

Previous namestranslocated promoter region (to activated MET oncogene)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Thyroid gland papillary carcinoma

Autosomal recessive non-syndromic intellectual disability

COVID-19

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Nucleoporins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.