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TREH

Gene

trehalase

HGNCHGNC:12266EnsemblENSG00000118094NCBI Gene11181
Locus: gene with protein productLocation: 11q23.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTRE · TREA · MGC129621
View full nomenclature history (6)
Alias symbolsTRE, TREA, MGC129621
Previous namestrehalase (brush-border membrane glycoprotein)
Alias namesalpha,alpha-trehalase, alpha,alpha-trehalose glucohydrolase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Arthritis, Rheumatoid
Neurodegenerative Diseases
Eye Infections
Hearing Loss
Hypothyroidism
Lupus Erythematosus, Systemic
Celiac Disease
Glioma
Primary biliary cholangitis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Glycoside hydrolase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.