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U2AF2

Gene

U2 small nuclear RNA auxiliary factor 2

HGNCHGNC:23156EnsemblENSG00000063244NCBI Gene11338
Locus: gene with protein productLocation: 19q13.42

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asU2AF65
View full nomenclature history (5)
Alias symbolsU2AF65
Previous namesU2 (RNU2) small nuclear RNA auxiliary factor 2
Alias namesU2 small nuclear ribonucleoprotein auxiliary factor (65kD), splicing factor U2AF 65 kD subunit, U2 snRNP auxiliary factor large subunit

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodevelopmental Disorders
Genetic Diseases, Inborn
Leukemia, Myeloid, Acute
Dengue
Neurodegenerative Diseases
Stroke
Alcohol drinking

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

RNA binding motif containingSpliceosomal A complexSpliceosomal E complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.