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UBR5

Gene

ubiquitin protein ligase E3 component n-recognin 5

HGNCHGNC:16806EnsemblENSG00000104517NCBI Gene51366
Locus: gene with protein productLocation: 8q22.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asEDD1 · DD5 · HYD · EDD · KIAA0896
View full nomenclature history (6)
Previous symbolsEDD1
Alias symbolsDD5, HYD, EDD, KIAA0896
Previous namesE3 ubiquitin protein ligase, HECT domain containing, 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Complex neurodevelopmental disorder
Neurodevelopmental Disorders
Alcohol drinking
Lymphoma, Mantle-Cell
Cutaneous melanoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Ubiquitin protein ligase E3 component n-recogninsHECT domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.