VTCN1

Gene

V-set domain containing T cell activation inhibitor 1

HGNCHGNC:28873 EnsemblENSG00000134258 NCBI Gene79679

Locus: gene with protein productLocation: 1p13.1-p12

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

V-set domain-containing T-cell activation inhibitor 1Q7Z7D3

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asB7-H4 · FLJ22418 · B7S1 · B7x · B7H4

View full nomenclature history (7)

Alias symbolsB7-H4, FLJ22418, B7S1, B7x, B7H4

Alias namesB7 family member, H4, B7 superfamily member 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Alcohol drinking

Helicobacter Infections

Kidney Diseases

Neoplasms

Carcinoma, Non-Small-Cell Lung

Carcinoma, Hepatocellular

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

V-set domain containingB7 family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.