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YWHAB

Gene

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta

HGNCHGNC:12849EnsemblENSG00000166913NCBI Gene7529
Locus: gene with protein productLocation: 20q13.12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asYWHAA
View full nomenclature history (5)
Previous symbolsYWHAA
Previous namestyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide
Alias names14-3-3 beta, 14-3-3 alpha

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neoplasms
Noonan syndrome
Cardiomyopathy, Hypertrophic
Costello syndrome
Neurodegenerative Diseases
COVID-19
Severe Acute Respiratory Syndrome
Parkinson's Disease
Alzheimer's Disease
Lysosomal Storage Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

14-3-3 phospho-serine/phospho-threonine binding proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.