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ZUP1

Gene

zinc finger containing ubiquitin peptidase 1

HGNCHGNC:21224EnsemblENSG00000153975NCBI Gene221302
Locus: gene with protein productLocation: 6q22.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asZUFSP · C6orf113 · dJ412I7.3
View full nomenclature history (6)
Previous symbolsZUFSP, C6orf113
Alias symbolsdJ412I7.3
Previous nameschromosome 6 open reading frame 113, zinc finger with UFM1 specific peptidase domain, zinc finger containing ubiquitin peptidase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Ovarian dysfunction
Ischemic Attack, Transient
Colitis
Neoplasms
Infections
Melanoma
Carcinoma, Hepatocellular
Glioblastoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers C2H2-typeZUP1 deubiquitinase

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.