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Disease

Neural Tube Defects

Late-stage therapeutic developmentEmerging research
MeSHNeural Tube Defects
1
Publications
6
Clinical trials
2014
Latest publication
Latest activity
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Recent clinical, regulatory, research and industry developments relating to this disease.

Neural tube defects.

Research2014-01-01Annual review of neuroscience

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Clinical trials

6 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
6
All trials
0
Active
2
Late-stage
5
Completed
Recently completed

Post Transplant Infusion of Allogeneic Cytokine Induced Killer Cells as Consolidative Therapy After Non-Myeloablative Allogeneic Transplantation in Patients With Myelodysplasia or Myeloproliferative Disorders

Phase 2 · Completed · Everett Meyer

Prevention of Neural Tube Defects by Inositol in Conjunction With Folic Acid (PONTI Study)

Phase 1 · Completed · Institute of Child Health

Multi-Center, Randomized, Double-Blind Active-Controlled, Parallel Group Study to Investigate Plasma Folate, Red Blood Cell Folate and Homocysteine Levels During a 24 Week Oral Administration of an OC Containing Folate Compared to OC Alone

Phase 3 · Completed · Bayer

Efficacy of Weekly Versus Daily Folic Acid Supplementation

N/A · Completed · Emory University

Blood Folate and Homocysteine Levels Following Administration of Folic Acid According to Different Daily Dosing Schedules:a Simulation of Food Fortification

N/A · Completed · Centers for Disease Control and Prevention

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

Neural tube defects.

Annual review of neuroscience · 2014 · 441 cites
Recent publications

Neural tube defects.

Annual review of neuroscience · 2014 · 441 cites
Major themes1
  • Neural Tube Defects1
Leading journals1
  • Annual review of neuroscience1
Leading researchers2
  • Copp AJ1
  • Greene ND1
Affiliations (unnormalised)1
  • Newlife Birth Defects Research Center1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)

Identifiers
MeSHNeural Tube Defects
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.