PARD3

Gene

par-3 family cell polarity regulator

HGNCHGNC:16051 EnsemblENSG00000148498 NCBI Gene56288

Locus: gene with protein productLocation: 10p11.22-p11.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPARD-3 · PAR-3 · PAR3 · PARD3A · Bazooka · Baz · ASIP · PPP1R118

View full nomenclature history (13)

Alias symbolsPARD-3, PAR-3, PAR3, PARD3A, Bazooka, Baz, ASIP, PPP1R118

Previous namespar-3 (partitioning defective 3, C.elegans) homolog, par-3 partitioning defective 3 homolog (C. elegans)

Alias namesatypical PKC isotype-specific interacting protein, par-3 family cell polarity regulator alpha, protein phosphatase 1, regulatory subunit 118

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Protein phosphatase 1 regulatory subunitsPDZ domain containingPar-3 family cell polarity regulators

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-10-23.

Open TargetsGene–disease associations from the Open Targets Platform.