Serotonin
In clinical developmentAlso known as 3-(2-Aminoethyl)-1H-indol-5-ol, 5-HT, 5-HT - 5-hydroxytryptamine, 5-Hydroxytryptamine+5 more
3-(2-Aminoethyl)-1H-indol-5-ol, 5-HT, 5-HT - 5-hydroxytryptamine, 5-Hydroxytryptamine, 5-hydroxy tryptamine, Enteramine, thrombocytin, thrombotonin, sérotonine.
Recent clinical, regulatory, research and industry developments relating to this drug.
Columbia scientists discover surprising link between serotonin and heart valve disease
Synaptic Interactions Between Serotonergic and Dopaminergic Systems in Parkinson's Disease.
Microglia regulate motor neuron plasticity via reciprocal fractalkine and adenosine signaling.
The Role of Gut Microbiome in Sleep Quality and Health: Dietary Strategies for Microbiota Support.
Molecular Design of SERTlight: A Fluorescent Serotonin Probe for Neuronal Labeling in the Brain.
Serotonin Signaling through Lipid Membranes.
Gut bacteria-derived serotonin promotes immune tolerance in early life.
Serotonin modulates excitatory synapse maturation in the developing prefrontal cortex.
Beyond the 5-HT<sub>2A</sub> Receptor: Classic and Nonclassic Targets in Psychedelic Drug Action.
Profile
Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.
Clinical trials
The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.
Recent completions
Trials that read out recently, adding to the completed evidence base.
Research activity
Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.
Major research themes8
Journals, researchers & institutions
- International journal of molecular sciences4
- Nature communications3
- Molecular psychiatry2
- Nutrients2
- ACS chemical neuroscience1
- Archives of toxicology1
- Aguilar-Valles A2
- Bonniwell EM2
- Lewis V2
- McCorvy JD2
- Wang J2
- Abizaid A1
- Amendola S1
- Amir M1
- Carleton University2
- Medical College of Wisconsin2
- University of California2
- Aarhus University1
- Autonoma de Madrid University-Cajal Institute1
- Baylor College of Medicine1
Related diseases
Regulator-approved indications and conditions co-mentioned with this drug across the research literature. Number shows shared papers.
Related drugs
Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).
Studied across 5 of the same disease areas as Serotonin in the shared literature.
Studied across 4 of the same disease areas as Serotonin in the shared literature.
Studied across 5 of the same disease areas as Serotonin in the shared literature.
Studied across 4 of the same disease areas as Serotonin in the shared literature.
Studied across 4 of the same disease areas as Serotonin in the shared literature.
Studied across 3 of the same disease areas as Serotonin in the shared literature.
Studied across 3 of the same disease areas as Serotonin in the shared literature.
Studied across 2 of the same disease areas as Serotonin in the shared literature.
- RxNorm (U.S. National Library of Medicine) — drug identity
- ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
- Europe PMC — research literature
- ClinicalTrials.gov — clinical trials