Drug

Tetracycline

In clinical development

ClassBacterial 70S ribosome inhibitorEmerging researchLate-stage development

Also known as Ala-Tet, Brodspec, Emtet-500, Pylera+17 more

Ala-Tet, Brodspec, Emtet-500, Pylera, Robitet 500, Tetra 500, Tetracap, Tetracon, Tetrazyklin, Tsiklomitsin, Viabecline, Vitastem, Achromycin, Panmycin, Sumycin, Topicycline, Tetracyclin, Tétracycline, (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide, Tetracycline Hydrochloride, Tetracyclinum.

RxNorm10395 ChEMBLCHEMBL1440 ATCD06AA04 ATCS03AA02 ATCS01AA09 ATCS02AA08 ATCA01AB13 ATCJ01AA07UNIIF8VB5M810T

Research papers

Active clinical trials

Protein targets

Latest activity

beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Fe-doped BiVO4/g-C3N4 heterojunction for efficient tetracycline degradation under low-intensity UV irradiation

Industry2026-07-23Nature — Environmental Sciences

Helicobacter Pylori Eradication and Follow-up in Zhongshan Hospital

Clinical trial2026-06-30Primary completion · ClinicalTrials.gov

T4 - Tetracycline Treatment Tolerability Trial A Pilot Study Examining the Feasibility and Tolerability of Tetracycline Therapy in Post-Treatment Lyme Disease (PTLD)

Clinical trial2026-06-09Completed · ClinicalTrials.gov

Randomized Controlled Trial of Weekly Oral Isotretinoin vs. Oral Tetracyclines for the Treatment of Moderate Acne Vulgaris

Clinical trial2026-05-18Results expected Q1 2027 · ClinicalTrials.gov

Efficacy and Safety of Tegoprazan-Based Dual, Triple, and Quadruple Therapies as First-Line Regimens for Helicobacter Pylori Eradication: A Prospective Randomized Controlled Trial

Clinical trial2026-03-10Completed · ClinicalTrials.gov

Efficacy and Safety of Saccharomyces Boulardii Combined With Bismuth Quadruple Therapy for Helicobacter Pylori Rescue Treatment: A Prospective, Multicenter, Randomized Controlled Trial

Clinical trial2025-12-02Results expected Q3 2026 · ClinicalTrials.gov

Doxycycline-containing Bismuth Quadruple Therapy for Helicobacter Pylori Rescue Treatment: a Randomized Controlled Trial

Clinical trial2025-10-10Primary completion · ClinicalTrials.gov

Phase II, Open-label, Single Blind, Randomised Clinical Trial With Tetracycline as a Prophylaxis for Rash and Dermatological Recommendations Versus Dermatological Recommendations in Patients With NSCLC Receiving Treatment With BIBW 2992

Clinical trial2025-05-11Results posted · ClinicalTrials.gov

Rifabutin-containing Triple Therapy for Helicobacter Pylori Rescue Treatment: a Randomized Controlled Trial

Clinical trial2025-01-31Completed · ClinicalTrials.gov

Sanitation, Water, and Instruction in Face-washing for Trachoma I/II

Clinical trial2024-12-31Completed · ClinicalTrials.gov

Rescue Therapy for Helicobacter Pylori Eradication: A Randomized and Non-inferiority Trail of Vonorazon and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy

Clinical trial2024-08-30Completed · ClinicalTrials.gov

Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal.

Research1999-01-01The Journal of clinical investigation

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name

Tetracycline

Aliases & brands

Ala-TetBrodspecEmtet-500PyleraRobitet 500Tetra 500TetracapTetraconTetrazyklinTsiklomitsinViabeclineVitastemAchromycinPanmycinSumycinTopicyclineTetracyclinTétracycline(4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamideTetracycline HydrochlorideTetracyclinum

RxNorm CUI

10395

ChEMBL ID

CHEMBL1440

ATC codes

D06AA04S03AA02S01AA09S02AA08A01AB13J01AA07

UNII

F8VB5M810T

Primary mechanism

Bacterial 70S ribosome inhibitor

Pharmacology & targets

55 targets

Known molecular targets and mechanisms supported by curated pharmacology databases.

Small ribosomal subunit protein uS2

rpsB · P0A7V0