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ADAMTS8

Gene

ADAM metallopeptidase with thrombospondin type 1 motif 8

HGNCHGNC:224EnsemblENSG00000134917NCBI Gene11095
Locus: gene with protein productLocation: 11q24.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMETH2 · FLJ41712 · ADAM-TS8
View full nomenclature history (4)
Alias symbolsMETH2, FLJ41712, ADAM-TS8
Previous namesa disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Glaucoma, Open-Angle
Aortic Aneurysm
Glaucoma
Aneurysm
Hypertension
Idiopathic Pulmonary Fibrosis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

ADAM metallopeptidases with thrombospondin type 1 motif

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.