AP1S3

Gene

adaptor related protein complex 1 subunit sigma 3

HGNCHGNC:18971 EnsemblENSG00000152056 NCBI Gene130340

Locus: gene with protein productLocation: 2q36.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known assigma1C

View full nomenclature history (3)

Alias symbolssigma1C

Previous namesadaptor related protein complex 1 sigma 3 subunit

Alias namesAP-1 complex subunit sigma 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Generalized pustular psoriasis

Childhood onset asthma

Pneumonia, Viral

Urolithiasis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Adaptor related protein complex 1

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.

Open TargetsGene–disease associations from the Open Targets Platform.