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CD226

Gene

CD226 molecule

HGNCHGNC:16961EnsemblENSG00000150637NCBI Gene10666
Locus: gene with protein productLocation: 18q22.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDNAM-1 · DNAM1 · PTA1 · TLiSA1
View full nomenclature history (5)
Alias symbolsDNAM-1, DNAM1, PTA1, TLiSA1
Previous namesCD226 antigen

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hypothyroidism
Diabetes Mellitus, Type 1
Primary biliary cholangitis
Arthritis, Rheumatoid
Lupus Erythematosus, Systemic
Autoimmune Diseases
Myxedema
Asthma
Inflammatory Bowel Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesV-set domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.