Back to discover

CR2

Gene

complement C3d receptor 2

HGNCHGNC:2336EnsemblENSG00000117322NCBI Gene1380
Locus: gene with protein productLocation: 1q32.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCD21 · C3DR
View full nomenclature history (5)
Alias symbolsCD21, C3DR
Previous namescomplement component (3d/Epstein Barr virus) receptor 2, complement component 3d receptor 2
Alias namesEpstein-Barr virus receptor

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Common variable immunodeficiency
Lupus Erythematosus, Systemic
Alcohol drinking
Urolithiasis
Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesSushi domain containingComplement system regulators and receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.