FASLG

Gene

Fas ligand

HGNCHGNC:11936 EnsemblENSG00000117560 NCBI Gene356

Locus: gene with protein productLocation: 1q24.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Tumor necrosis factor ligand superfamily member 6P48023

Protein · therapeutic target

Clinical-stage target · 1 candidate in clinical development

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asAPT1LG1 · TNFSF6 · FasL · CD178

View full nomenclature history (6)

Previous symbolsAPT1LG1, TNFSF6

Alias symbolsFasL, CD178

Previous namestumor necrosis factor (ligand) superfamily, member 6, Fas ligand (TNF superfamily, member 6)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Lupus Erythematosus, Systemic

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesTumor necrosis factor superfamilyDeath inducing signaling complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.