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GTF2F1

Gene

general transcription factor IIF subunit 1

HGNCHGNC:4652EnsemblENSG00000125651NCBI Gene2962
Locus: gene with protein productLocation: 19p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTFIIF · BTF4 · RAP74 · TF2F1
View full nomenclature history (6)
Alias symbolsTFIIF, BTF4, RAP74, TF2F1
Previous namesgeneral transcription factor IIF, polypeptide 1 (74kD subunit), general transcription factor IIF, polypeptide 1, 74kDa

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

HIV Infections
Neurodegenerative Diseases
Dengue
Influenza, Human
Stroke
Arthritis, Rheumatoid
Lupus Erythematosus, Systemic

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

MicroRNA protein coding host genesGeneral transcription factor IIF complex subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.