IFIT3

Gene

interferon induced protein with tetratricopeptide repeats 3

HGNCHGNC:5411 EnsemblENSG00000119917 NCBI Gene3437

Locus: gene with protein productLocation: 10q23.31

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asIFIT4 · ISG60 · RIG-G · CIG-49 · IFI60 · GARG-49 · IRG2

View full nomenclature history (9)

Previous symbolsIFIT4

Alias symbolsISG60, RIG-G, CIG-49, IFI60, GARG-49, IRG2

Previous namesinterferon-induced protein with tetratricopeptide repeats 4, interferon-induced protein with tetratricopeptide repeats 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Lupus Erythematosus, Systemic

Neoplasms

Scleroderma, Systemic

Esophageal Squamous Cell Carcinoma

Lung carcinoma

Lung Neoplasms

Acute promyelocytic leukemia

Myocardial Infarction

Carcinoma, Non-Small-Cell Lung

Pancreatic Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Tetratricopeptide repeat domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.