MUC1

Gene

mucin 1, cell surface associated

HGNCHGNC:7508 EnsemblENSG00000185499 NCBI Gene4582

Locus: gene with protein productLocation: 1q22

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Mucin-1P15941

Protein · therapeutic target

Clinical-stage target · 10 candidates in clinical development

Member of “Mucins” · 7 related family papers (context, not papers about this gene)

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPUM · MCKD1 · CD227 · PEM · ADMCKD · ADMCKD1 · MCKD · MCD · KL-6 · EMA · Ca15-3

View full nomenclature history (14)

Previous symbolsPUM, MCKD1

Alias symbolsCD227, PEM, ADMCKD, ADMCKD1, MCKD, MCD, KL-6, EMA, Ca15-3

Previous namesmedullary cystic kidney disease 1 (autosomal dominant), mucin 1, transmembrane

Alias namesepithelial membrane antigen

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Carcinoma, Non-Small-Cell Lung

Inflammatory Bowel Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesMucins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.

Open TargetsGene–disease associations from the Open Targets Platform.