NSMCE4A

Gene

NSE4A component of SMC5/6 complex

HGNCHGNC:25935 EnsemblENSG00000107672 NCBI Gene54780

Locus: gene with protein productLocation: 10q26.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC10orf86 · FLJ20003 · bA500G22.3 · NSE4A

View full nomenclature history (8)

Previous symbolsC10orf86

Alias symbolsFLJ20003, bA500G22.3, NSE4A

Previous namesNSE4 homolog A, SMC5-SMC6 complex component, chromosome 10 open reading frame 86, non-SMC element 4 homolog A (S. cerevisiae), NSE4 homolog, SMC5-SMC6 complex component A

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Dupuytren Contracture

Alzheimer's Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

SMC5/6 complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-06-16.

Open TargetsGene–disease associations from the Open Targets Platform.