PCLO

Gene

piccolo presynaptic cytomatrix protein

HGNCHGNC:13406 EnsemblENSG00000186472 NCBI Gene27445

Locus: gene with protein productLocation: 7q21.11

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDKFZp779G1236 · KIAA0559 · ACZ

View full nomenclature history (5)

Alias symbolsDKFZp779G1236, KIAA0559, ACZ

Previous namespiccolo (presynaptic cytomatrix protein)

Alias namesaczonin

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Major depressive disorder

Alcohol drinking

Diabetes Mellitus, Type 1

Irritable Bowel Syndrome

Sleep Initiation and Maintenance Disorders

Schizophrenia

Stress Disorders, Post-Traumatic

Attention Deficit Disorder with Hyperactivity

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

C2 domain containingPDZ domain containingZinc fingers PCLO-type

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.