PRDM1

Gene

PR/SET domain 1

HGNCHGNC:9346 EnsemblENSG00000057657 NCBI Gene639

Locus: gene with protein productLocation: 6q21

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

PR domain zinc finger protein 1O75626

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asBLIMP1 · PRDI-BF1 · Blimp-1

View full nomenclature history (6)

Previous symbolsBLIMP1

Alias symbolsPRDI-BF1, Blimp-1

Previous namesPR domain containing 1, with ZNF domain, PR domain 1, B lymphocyte-induced maturation protein 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Colitis, Ulcerative

Inflammatory Bowel Diseases

Lymphoma, Large B-Cell, Diffuse

Alopecia

Neurodegenerative Diseases

Crohn's Disease

Psoriasis

Melanoma

Primary central nervous system lymphoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers C2H2-typePR/SET domain familyPutative lysine methyltransferases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-11-03.

Open TargetsGene–disease associations from the Open Targets Platform.