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PSME4

Gene

proteasome activator subunit 4

HGNCHGNC:20635EnsemblENSG00000068878NCBI Gene23198
Locus: gene with protein productLocation: 2p16.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPA200 · KIAA0077
View full nomenclature history (3)
Alias symbolsPA200, KIAA0077
Previous namesproteasome (prosome, macropain) activator subunit 4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Alzheimer's Disease
Osteoarthritis, Knee
Intestinal Obstruction
Liver Diseases
Aortic Diseases
Smoking initiation

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

ProteasomeArmadillo like helical domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.