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SLC4A4

Gene

solute carrier family 4 member 4

HGNCHGNC:11030EnsemblENSG00000080493NCBI Gene8671
Locus: gene with protein productLocation: 4q13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSLC4A5 · NBC1 · HNBC1 · NBC2 · pNBC · hhNMC · kNBC1 · KNBC · NBCe1
View full nomenclature history (14)
Previous symbolsSLC4A5
Alias symbolsNBC1, HNBC1, NBC2, pNBC, hhNMC, kNBC1, KNBC, NBCe1
Previous namessolute carrier family 4, sodium bicarbonate cotransporter, member 4, solute carrier family 4 (sodium bicarbonate cotransporter), member 4
Alias namesElectrogenic sodium bicarbonate cotransporter 1, kidney type Na+/HCO3- cotransporter, pancreatic sodium bicarbonate cotransporter

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Atrial Fibrillation
Alcohol drinking
Joint Diseases
Endocrine System Diseases
Idiopathic pulmonary arterial hypertension
Ovarian neoplasm

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Solute carrier family 4

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.