Back to discover

SPTLC3

Gene

serine palmitoyltransferase long chain base subunit 3

HGNCHGNC:16253EnsemblENSG00000172296NCBI Gene55304
Locus: gene with protein productLocation: 20p12.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC20orf38 · SPTLC2L · LCB2B · FLJ11112 · hLCB2b
View full nomenclature history (7)
Previous symbolsC20orf38, SPTLC2L
Alias symbolsLCB2B, FLJ11112, hLCB2b
Previous nameschromosome 20 open reading frame 38, serine palmitoyltransferase, long chain base subunit 2-like (aminotransferase 2)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Alcohol drinking
Cholelithiasis
Male reproductive organ cancer
Stroke
Ovarian dysfunction
Spondylitis, Ankylosing
Liver Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Serine palmitoyltransferase long chain base subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.