Back to discover

TTLL1

Gene

TTL family tubulin polyglutamylase complex subunit L1

HGNCHGNC:1312EnsemblENSG00000100271NCBI Gene25809
Locus: gene with protein productLocation: 22q13.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC22orf7 · PGs3 · TPGS3
View full nomenclature history (7)
Previous symbolsC22orf7
Alias symbolsPGs3, TPGS3
Previous namestubulin tyrosine ligase-like 1, tubulin tyrosine ligase-like family member 1, tubulin tyrosine ligase like 1
Alias namespolyglutamylase subunit 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Alcohol drinking
Stroke
Prostatic Neoplasms
Primary Ovarian Insufficiency
Prostate carcinoma
Kartagener Syndrome
Familial focal epilepsy with variable foci
Spermatogenic failure

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Tubulin tyrosine ligase familyTubulin polyglutamylase complex subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.