WFIKKN2

Gene

WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2

HGNCHGNC:30916 EnsemblENSG00000173714 NCBI Gene124857

Locus: gene with protein productLocation: 17q21.33

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asWFIKKNRP · WFDC20B

View full nomenclature history (3)

Alias symbolsWFIKKNRP, WFDC20B

Alias namesWAP four-disulfide core domain 20B

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Osteoarthritis, Hip

Osteoarthritis, Knee

Total joint arthroplasty

Neurodegenerative Diseases

Amyotrophic Lateral Sclerosis

Congenital myasthenic syndromes

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

WAP four-disulfide core domain containingI-set domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.