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Disease

Blood Coagulation Disorders

Late-stage therapeutic developmentEmerging research
MeSHBlood Coagulation Disorders
3
Publications
10
Clinical trials
3
Related conditions
2020
Latest publication
Latest activity
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Recent clinical, regulatory, research and industry developments relating to this disease.

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Clinical trials

9 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
10
All trials
0
Active
9
Late-stage
6
Completed
Late-stage studies

Does Plasma Reduce Bleeding in Patients Undergoing Invasive Procedures

Phase 3 · Completed · Rutgers, The State University of New Jersey

A Phase IV, Randomized, Single Center, Parallel Group Trial of Human Fibrinogen Concentrate (Haemocomplettan) in the Treatment of Dilutional Coagulopathy During Major Pediatric Surgery

Phase 4 · Completed · University Children's Hospital, Zurich

The Hospital and Economics CERT: Project 1: The Clinical and Economic Implications of Genetic Testing for Warfarin Management

Phase 4 · Completed · University of Chicago

A Two Part Randomized Cross-Over Trial to Evaluate the Pharmacokinetics, Efficacy, and Safety Profile of Plasma Protein-Free Recombinant FVIII Formulated With Sucrose (BAY81-8973) in Previously Treated Subjects With Severe Hemophilia A Under Prophylaxis Therapy

Phase 3 · Completed · Bayer

An Open-label, Randomized, Multicenter Phase IIIb Study to Assess the Efficacy, Safety and Tolerance of BERIPLEX® P/N Compared With Plasma for Rapid Reversal of Coagulopathy Induced by Coumarin Derivatives in Subjects With Acute Major Bleeding

Phase 3 · Completed · CSL Behring

Anticoagulant Clinic-based Shared-care Versus Usual Cate Management of Vitamin K Antagonist Therapy : the Open, Randomized Multicenter Study

Phase 4 · Completed · University Hospital, Toulouse
Recently completed

Does Plasma Reduce Bleeding in Patients Undergoing Invasive Procedures

Phase 3 · Completed · Rutgers, The State University of New Jersey

A Phase IV, Randomized, Single Center, Parallel Group Trial of Human Fibrinogen Concentrate (Haemocomplettan) in the Treatment of Dilutional Coagulopathy During Major Pediatric Surgery

Phase 4 · Completed · University Children's Hospital, Zurich

The Hospital and Economics CERT: Project 1: The Clinical and Economic Implications of Genetic Testing for Warfarin Management

Phase 4 · Completed · University of Chicago

A Two Part Randomized Cross-Over Trial to Evaluate the Pharmacokinetics, Efficacy, and Safety Profile of Plasma Protein-Free Recombinant FVIII Formulated With Sucrose (BAY81-8973) in Previously Treated Subjects With Severe Hemophilia A Under Prophylaxis Therapy

Phase 3 · Completed · Bayer

An Open-label, Randomized, Multicenter Phase IIIb Study to Assess the Efficacy, Safety and Tolerance of BERIPLEX® P/N Compared With Plasma for Rapid Reversal of Coagulopathy Induced by Coumarin Derivatives in Subjects With Acute Major Bleeding

Phase 3 · Completed · CSL Behring

Anticoagulant Clinic-based Shared-care Versus Usual Cate Management of Vitamin K Antagonist Therapy : the Open, Randomized Multicenter Study

Phase 4 · Completed · University Hospital, Toulouse

Research activity

3 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20192020
Leading journals3
  • Blood1
  • International journal of molecular sciences1
  • Nature medicine1
Leading researchers8
  • Azevedo-Quintanilha IG1
  • Barreto EA1
  • Bozza FA1
  • Bozza PT1
  • Butler D1
  • Cai S1
  • De Freitas JK1
  • Foox J1
Affiliations (unnormalised)6
  • Biomedical Research Center of South China1
  • Center for Technological Development in Health (CDTS)1
  • Columbia University1
  • D'Or Institute for Research and Education1
  • Hasso Plattner Institute for Digital Health at Mount Sinai1
  • Herbert Irving Comprehensive Cancer Center1

Related conditions

3 matches

Diseases frequently studied alongside this one. Number shows shared papers.

Coronavirus Infections2COVID-192Pneumonia, Viral2

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions.

Identifiers
MeSHBlood Coagulation Disorders
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.