ANO2

Gene

anoctamin 2

HGNCHGNC:1183 EnsemblENSG00000047617 NCBI Gene57101

Locus: gene with protein productLocation: 12p13.31

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC12orf3 · TMEM16B

View full nomenclature history (6)

Previous symbolsC12orf3, TMEM16B

Previous nameschromosome 12 open reading frame 3, transmembrane protein 16B, anoctamin 2, calcium activated chloride channel

Alias namestransmembrane protein 16B (eight membrane-spanning domains)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Blood Coagulation Disorders

COVID-19

Venous Thromboembolism

Immune System Diseases

Intracranial Aneurysm

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Anoctamins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.