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Drug

Dextran Sulfate

In clinical development
Emerging researchEarly-to-mid developmentRising momentum
9
Research papers
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Rapamycin extenuates experimental colitis by modulating the gut microbiota.

Research2023-11-02Journal of gastroenterology and hepatology

Male-Biased Gut Microbiome and Metabolites Aggravate Colorectal Cancer Development.

Research2023-07-03Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Dextran Sulfate
RxNorm CUI
40068

Clinical trials

3 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
3
registered trials across all phases
LATEST COMPLETION 1991
1
Late-stage (III+)
3
Completed
PHASE DISTRIBUTIONn = 3
Phase 12Phase N / A1

Recent completions

Trials that read out recently, adding to the completed evidence base.

Research activity

9 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20192024
Most influential
Recent papers
Major research themes8
Gastrointestinal Microbiome7Colitis5Colorectal Neoplasms2Dextran Sulfate2Dysbiosis2Bacteria1Carrier Proteins1Colon1
Journals, researchers & institutions
Top journals
  • Gastroenterology2
  • Advanced science (Weinheim, Baden-Wurttemberg, Germany)1
  • Cell death & disease1
  • Gut microbes1
  • Journal of gastroenterology and hepatology1
  • Microbiome1
Leading researchers
  • Han D3
  • Wang J3
  • Zhang X3
  • Pang J2
  • Zhang G2
  • Zhang S2
  • Zhang Y2
  • Ambat A1
Leading institutions
free-text, unnormalised
  • Oklahoma State University2
  • State Key Laboratory of Animal Nutrition and Feeding2
  • Albert Ludwigs University of Freiburg1
  • College of Biomedicine and Health1
  • College of Food Science and Technology1
  • College of Veterinary Medicine1

Related diseases

6 conditions

Regulator-approved indications and conditions co-mentioned with this drug across the research literature. Number shows shared papers.

Related drugs

4 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Studied across 4 of the same disease areas as Dextran Sulfate in the shared literature.

4 shared diseases1 shared paper

Studied across 3 of the same disease areas as Dextran Sulfate in the shared literature.

3 shared diseases1 shared paper

Studied across 3 of the same disease areas as Dextran Sulfate in the shared literature.

3 shared diseases1 shared paper

Studied across 3 of the same disease areas as Dextran Sulfate in the shared literature.

3 shared diseases1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials