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Drug

Iron

In clinical development
Actively researchedLate-stage developmentCooling momentum
Also known as Eisen, Elemental Iron, Fe, Fe - Iron+6 more

Eisen, Elemental Iron, Fe, Fe - Iron, Ferrum, Hierro, Iron, elemental, Iron, reduced, Reduced iron, fer.

RxNorm90176UNIIE1UOL152H7
32
Research papers
6
Active clinical trials
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Restoring Iron Deficiency to Expand Blood Volume and Improve POTS

Clinical trial2025-12-11Results expected Q4 2026 · ClinicalTrials.gov

Microbial siderophores for One Health.

Research2025-06-03Trends in microbiology

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Iron
Aliases & brands
EisenElemental IronFeFe - IronFerrumHierroIron, elementalIron, reducedReduced ironfer
RxNorm CUI
90176
UNII
E1UOL152H7

Clinical trials

56 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
56
registered trials across all phases
LATEST COMPLETION 2025
6
Active studies
6
Recruiting
46
Late-stage (III+)
31
Completed
19
Discontinued
PHASE DISTRIBUTIONn = 56
Phase 1 / 23Phase 27Phase 2 / 31Phase 318Phase 417Phase N / A10

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Recent completions

Trials that read out recently, adding to the completed evidence base.

Research activity

32 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20032026
Most influential

Ferroptosis: past, present and future.

Cell death & disease · 2020 · 2,924 cites

Bacterial iron homeostasis.

FEMS microbiology reviews · 2003 · 1,836 cites

The role of oxidative stress in Parkinson's disease.

Journal of Parkinson's disease · 2013 · 1,292 cites

Nutrition and brain development in early life.

Nutrition reviews · 2014 · 638 cites
Recent papers
Major research themes8
Ferroptosis13Iron6Alzheimer Disease3Gastrointestinal Microbiome2Neoplasms2Neurodegenerative Diseases2Parkinson Disease2Trace Elements2
Journals, researchers & institutions
Top journals
  • International journal of molecular sciences4
  • Cell death & disease2
  • Molecular psychiatry2
  • Nutrients2
  • Advances in nutrition (Bethesda, Md.)1
  • Archives of toxicology1
Leading researchers
  • Bush AI2
  • Chen X2
  • Kang R2
  • Lei P2
  • Li J2
  • Li Z2
  • Liu J2
  • Liu Y2
Leading institutions
free-text, unnormalised
  • Department of Neurology and State Key Laboratory of Biotherapy2
  • School of Public Health2
  • UT Southwestern Medical Center2
  • Affiliated Qiqihar Hospital1
  • Affiliated Zhongshan Hospital of Dalian University1
  • Albert Einstein College of Medicine1

Related diseases

7 conditions

Regulator-approved indications and conditions co-mentioned with this drug across the research literature. Number shows shared papers.

Related drugs

8 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Studied across 9 of the same disease areas as Iron in the shared literature.

9 shared diseases1 shared paper

Studied across 7 of the same disease areas as Iron in the shared literature.

7 shared diseases2 shared papers

Studied across 5 of the same disease areas as Iron in the shared literature.

5 shared diseases3 shared papers

Studied across 8 of the same disease areas as Iron in the shared literature.

8 shared diseases1 shared paper

Studied across 6 of the same disease areas as Iron in the shared literature.

6 shared diseases2 shared papers

Studied across 5 of the same disease areas as Iron in the shared literature.

5 shared diseases2 shared papers

Studied across 6 of the same disease areas as Iron in the shared literature.

6 shared diseases1 shared paper

Studied across 6 of the same disease areas as Iron in the shared literature.

6 shared diseases1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials