Back to discover
Drug

Maytansine

Research stage
Emerging researchRising momentum

Also known as Maitansine.

9
Research papers
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

Mirvetuximab soravtansine-gynx: first antibody/antigen-drug conjugate (ADC) in advanced or recurrent ovarian cancer.

Research2024-04-01International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

HER2 Directed Antibody-Drug-Conjugates beyond T-DM1 in Breast Cancer.

Research2019-03-05International journal of molecular sciences

Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer.

Research2018-12-05The New England journal of medicine

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Maytansine
Aliases & brands
Maitansine
RxNorm CUI
2721221
ChEMBL ID
CHEMBL292702
UNII
14083FR882

Research activity

9 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
20082025
Most influential
Recent papers
Major research themes8
Ovarian Neoplasms3Breast Neoplasms2Immunoconjugates2Maytansine2Ado-Trastuzumab Emtansine1Antibodies, Monoclonal, Humanized1Antineoplastic Agents1Brain Neoplasms1
Journals, researchers & institutions
Top journals
  • Annals of oncology : official journal of the European Society for Medical Oncology1
  • Cancer research1
  • Gynecologic oncology1
  • International journal of gynecological cancer : official journal of the International Gynecological Cancer Society1
  • International journal of molecular sciences1
  • Journal of clinical oncology : official journal of the American Society of Clinical Oncology1
Leading researchers
  • Chari RV2
  • Coleman RL2
  • Lambert JM2
  • Oaknin A2
  • Anton A1
  • Arce-Salinas C1
  • Armetta J1
  • Ashfaque S1
Leading institutions
free-text, unnormalised
  • Aichi Cancer Center Hospital1
  • Asan Medical Center1
  • Bon Secours Hospital and Clinical Trials1
  • Breast Center1
  • Centre Leon Berard1
  • Centre Léon Bérard1

Related diseases

4 conditions

Regulator-approved indications and conditions co-mentioned with this drug across the research literature. Number shows shared papers.

Related drugs

3 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Studied across 5 of the same disease areas as Maytansine in the shared literature.

5 shared diseases3 shared papers

Studied across 4 of the same disease areas as Maytansine in the shared literature.

4 shared diseases1 shared paper

Studied across 3 of the same disease areas as Maytansine in the shared literature.

3 shared diseases1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature