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AQP1

Gene

aquaporin 1 (Colton blood group)

HGNCHGNC:633EnsemblENSG00000240583NCBI Gene358
Locus: gene with protein productLocation: 7p14.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCO · CHIP28
View full nomenclature history (6)
Previous symbolsCO
Alias symbolsCHIP28
Previous namesColton blood group, aquaporin 1 (channel-forming integral protein, 28kDa), aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group), aquaporin 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Osteoporosis
Nephrolithiasis
Bone Diseases
Fractures, Bone
Gout
Bladder calculus
Pre-Eclampsia
Urolithiasis
Hemolysis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

AquaporinsBlood group antigens

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.