CCL8

Gene

C-C motif chemokine ligand 8

HGNCHGNC:10635 EnsemblENSG00000108700 NCBI Gene6355

Locus: gene with protein productLocation: 17q12

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

C-C motif chemokine 8P80075

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSCYA8 · MCP-2 · HC14

View full nomenclature history (5)

Previous symbolsSCYA8

Alias symbolsMCP-2, HC14

Previous nameschemokine (C-C motif) ligand 8, small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Alcohol drinking

Neoplasms

Idiopathic Pulmonary Fibrosis

Lupus Erythematosus, Systemic

Inflammatory Bowel Diseases

Tuberculosis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Chemokine ligands

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.