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HELZ2

Gene

helicase with zinc finger 2

HGNCHGNC:30021EnsemblENSG00000130589NCBI Gene85441
Locus: gene with protein productLocation: 20q13.33

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPDIP1 · PRIC285 · KIAA1769
View full nomenclature history (6)
Alias symbolsPDIP1, PRIC285, KIAA1769
Previous nameshelicase with zinc finger 2, transcriptional coactivator
Alias namesperoxisomal proliferator activated receptor A interacting complex 285, PPARG-DBD-interacting protein 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Alcohol drinking
Inflammatory Bowel Diseases
Colitis
Enteritis
Colitis, Ulcerative
Pneumonia

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers CCCH-typeUPF1 like RNA helicases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.