HMBOX1

Gene

homeobox containing 1

HGNCHGNC:26137 EnsemblENSG00000147421 NCBI Gene79618

Locus: gene with protein productLocation: 8p21.1-p12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asHNF1LA · PBHNF · FLJ21616 · HOT1

View full nomenclature history (5)

Alias symbolsHNF1LA, PBHNF, FLJ21616, HOT1

Alias nameshomeobox telomere-binding protein 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Skin Diseases

Intestinal Obstruction

Esophageal Squamous Cell Carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

HNF class homeoboxes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.