ITGB1

Gene

integrin subunit beta 1

HGNCHGNC:6153 EnsemblENSG00000150093 NCBI Gene3688

Locus: gene with protein productLocation: 10p11.22

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Integrin beta-1P05556

Protein · therapeutic target

Clinically validated target · 1 approved medicine against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asFNRB · MSK12 · MDF2 · CD29 · GPIIA

View full nomenclature history (6)

Previous symbolsFNRB, MSK12, MDF2

Alias symbolsCD29, GPIIA

Previous namesintegrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Multiple Sclerosis

Crohn's Disease

Virus Diseases

Multiple Sclerosis, Relapsing-Remitting

Placental abruption

COVID-19

Diabetes Mellitus, Type 1

Musculoskeletal Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesIntegrin beta subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.

Open TargetsGene–disease associations from the Open Targets Platform.