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KBTBD8

Gene

kelch repeat and BTB domain containing 8

HGNCHGNC:30691EnsemblENSG00000163376NCBI Gene84541
Locus: gene with protein productLocation: 3p14.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTA-KRP · KIAA1842
View full nomenclature history (4)
Alias symbolsTA-KRP, KIAA1842
Previous nameskelch repeat and BTB (POZ) domain containing 8
Alias namesT-cell activation kelch repeat protein

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Glaucoma
Glaucoma, Open-Angle
Alcohol drinking
Diabetes Mellitus, Type 2
Respiratory Insufficiency
Fractures, Bone
Diabetes Mellitus
Placental abruption
Urolithiasis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

BTB domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.