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LRR1

Gene

leucine rich repeat protein 1

HGNCHGNC:19742EnsemblENSG00000165501NCBI Gene122769
Locus: gene with protein productLocation: 14q21.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPPIL5 · 4-1BBLRR · MGC20689 · LRR-1
View full nomenclature history (6)
Previous symbolsPPIL5
Alias symbols4-1BBLRR, MGC20689, LRR-1
Previous namespeptidylprolyl isomerase (cyclophilin)-like 5
Alias namesLRR-repeat protein 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Leukemia, Myeloid
Neurodegenerative Diseases
Esophageal Squamous Cell Carcinoma
Neuroblastoma
Sarcoma, Ewing
Corneal Neovascularization
Liver Diseases
Essential Tremor

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cyclophilin peptidylprolyl isomerases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-06-04.
Open TargetsGene–disease associations from the Open Targets Platform.