NFATC1

Gene

nuclear factor of activated T cells 1

HGNCHGNC:7775 EnsemblENSG00000131196 NCBI Gene4772

Locus: gene with protein productLocation: 18q23

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asNFATc · NFAT2 · NF-ATC

View full nomenclature history (5)

Alias symbolsNFATc, NFAT2, NF-ATC

Previous namesnuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1, nuclear factor of activated T-cells 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Osteoarthritis, Hip

Atrial Fibrillation

Hypothyroidism

Kidney Failure, Chronic

Renal Insufficiency

Neurodegenerative Diseases

Graves' Disease

Osteoarthritis, Knee

Myxedema

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Nuclear factors of activated T-cellsIPT domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.