ST8SIA4

Gene

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

HGNCHGNC:10871 EnsemblENSG00000113532 NCBI Gene7903

Locus: gene with protein productLocation: 5q21.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSIAT8D · PST · PST1

View full nomenclature history (6)

Previous symbolsSIAT8D

Alias symbolsPST, PST1

Previous namessialyltransferase 8 (alpha-2, 8-polysialytransferase) D, ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 4

Alias namesST8Sia IV

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Lupus Erythematosus, Systemic

Diabetes Mellitus

Hypotension

Diabetes Mellitus, Type 2

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

SialyltransferasesMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.