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Drug

Glucose

In clinical development
Actively researchedLate-stage developmentCooling momentum
Also known as D(+)-Glucose, D-glucose, DEXTROSE, DEXTROSE, UNSPECIFIED FORM+57 more

D(+)-Glucose, D-glucose, DEXTROSE, DEXTROSE, UNSPECIFIED FORM, Dex4, Dex4 Assorted Fruit, Dex4 Berry Twist, Dex4 Citrus Punch, Dex4 Fruit Punch, Dex4 Grape, Dex4 Mango Twist, Dex4 Natural Orange, Dex4 Orange, Dex4 Raspberry, Dextrosa, Dextrose 5%, Dextrose 5% and Plasma-Lyte 148, Dextrose, unspecified, Emetrol, Emetrol for Nausea, Enfamil Glucose, GlucoBurst, Glucose Ophthalmic, Grape sugar, Insta-Glucose, Ionosol-MB, Isolyte P, Isolyte S and 5% Dextrose, Isolyte S in 5 % Dextrose, Monojel, Navstel, Normosol-M, Normosol-R and 5% Dextrose, Normosol-R in 5 % Dextrose, Plasma-Lyte 56 and 5% Dextrose, Plasma-Lyte 56 in 5 % Dextrose, ReliOn Glucose, Glucosa, Glutose, Clinimix 4.25/10, Clinimix 4.25/25, Clinimix 4.25/5, Clinimix 5/15, Clinimix 5/20, Clinimix 5/25, Clinimix E 2.75/5, Clinimix E 4.25/10, Clinimix E 4.25/5, Clinimix E 5/15, Clinimix E 5/20, Clinimix E 5/25, Dextrose Anhydrous, Dextrose Monohydrate, Dextrose and Potassium Chloride, Dextrose/Potassium Chloride/Sodium Chloride, Dianeal Low Calcium 1.5, Dianeal Low Calcium 2.5, Dianeal Low Calcium 4.25, Dianeal PD-2/1.5, Dianeal PD-2/2.5, Dianeal PD-2/4.25.

97
Research papers
12
Active clinical trials
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this drug.

FDA clears Dexcom’s Stelo OTC glucose monitor for use with children

Regulatory2026-06-16Regulatory news · Fierce Biotech

Sleep Loss and Circadian Misalignment - Mechanisms of Insulin Resistance

Clinical trial2026-05-15Results expected Q1 2029 · ClinicalTrials.gov

Profile

Identifiers & mechanism

Canonical identifiers, marketed brand names and mechanism, resolved across RxNorm, ChEMBL and ATC.

Canonical name
Glucose
Aliases & brands
D(+)-GlucoseD-glucoseDEXTROSEDEXTROSE, UNSPECIFIED FORMDex4Dex4 Assorted FruitDex4 Berry TwistDex4 Citrus PunchDex4 Fruit PunchDex4 GrapeDex4 Mango TwistDex4 Natural OrangeDex4 OrangeDex4 RaspberryDextrosaDextrose 5%Dextrose 5% and Plasma-Lyte 148Dextrose, unspecifiedEmetrolEmetrol for NauseaEnfamil GlucoseGlucoBurstGlucose OphthalmicGrape sugarInsta-GlucoseIonosol-MBIsolyte PIsolyte S and 5% DextroseIsolyte S in 5 % DextroseMonojelNavstelNormosol-MNormosol-R and 5% DextroseNormosol-R in 5 % DextrosePlasma-Lyte 56 and 5% DextrosePlasma-Lyte 56 in 5 % DextroseReliOn GlucoseGlucosaGlutoseClinimix 4.25/10Clinimix 4.25/25Clinimix 4.25/5Clinimix 5/15Clinimix 5/20Clinimix 5/25Clinimix E 2.75/5Clinimix E 4.25/10Clinimix E 4.25/5Clinimix E 5/15Clinimix E 5/20Clinimix E 5/25Dextrose AnhydrousDextrose MonohydrateDextrose and Potassium ChlorideDextrose/Potassium Chloride/Sodium ChlorideDianeal Low Calcium 1.5Dianeal Low Calcium 2.5Dianeal Low Calcium 4.25Dianeal PD-2/1.5Dianeal PD-2/2.5Dianeal PD-2/4.25
RxNorm CUI
4850
ChEMBL ID
CHEMBL1222250
ATC codes
B05CX01C05BB56V06DC01V04CA02
UNII
IY9XDZ35W2

Clinical trials

101 trials

The current development programme across all trial phases — status mix, phase distribution and the late-stage studies shaping the evidence base.

Development programme
CLINICALTRIALS.GOV · LIVE REGISTRY
101
registered trials across all phases
LATEST COMPLETION 2026
12
Active studies
7
Recruiting
66
Late-stage (III+)
63
Completed
26
Discontinued
PHASE DISTRIBUTIONn = 101
Early Phase 16Phase 117Phase 1 / 22Phase 210Phase 2 / 33Phase 37Phase 424Phase N / A32

Late-stage studies

Phase III+ trials still open or recently active — where late-stage evidence is being generated.

Recent completions

Trials that read out recently, adding to the completed evidence base.

Research activity

97 papers

Key research shaping understanding of this drug, combining the latest publications with the most influential evidence.

Publications over time
19942026
Most influential

TLR4 links innate immunity and fatty acid-induced insulin resistance.

The Journal of clinical investigation · 2006 · 2,658 cites

Obesity and insulin resistance.

The Journal of clinical investigation · 2000 · 2,155 cites

Glucagon-like peptide 1 (GLP-1).

Molecular metabolism · 2019 · 1,239 cites

The Pathophysiology of Gestational Diabetes Mellitus.

International journal of molecular sciences · 2018 · 1,064 cites
Recent papers
Major research themes8
Diabetes Mellitus, Type 219Glucose11Insulin Resistance8Cardiovascular Diseases5Energy Metabolism5Islets of Langerhans4Lipid Metabolism4Neurons4
Journals, researchers & institutions
Top journals
  • International journal of molecular sciences10
  • Nature communications7
  • The Journal of clinical investigation6
  • Frontiers in endocrinology5
  • Cardiovascular diabetology4
  • Nutrients4
Leading researchers
  • Li Y3
  • Müller TD3
  • Nauck MA3
  • Reimann F3
  • Yang M3
  • Zhang H3
  • Ashrafi G2
  • Bäckhed F2
Leading institutions
free-text, unnormalised
  • School of Medicine5
  • German Center for Diabetes Research (DZD)3
  • Institute for Diabetes and Obesity3
  • Novo Nordisk Foundation Center for Basic Metabolic Research3
  • Diabetes Center Bochum-Hattingen2
  • Duke University Medical Center2

Related diseases

12 conditions

Regulator-approved indications and conditions co-mentioned with this drug across the research literature. Number shows shared papers.

Related drugs

8 matches

Drugs sharing diseases, protein targets and literature with this one. Ranked by graph evidence (shared targets + diseases weighted above co-mentions).

Studied across 35 of the same disease areas as Glucose in the shared literature.

27 shared papers35 shared diseases

Studied across 16 of the same disease areas as Glucose in the shared literature.

16 shared diseases7 shared papers

Studied across 18 of the same disease areas as Glucose in the shared literature.

18 shared diseases6 shared papers

Studied across 16 of the same disease areas as Glucose in the shared literature.

16 shared diseases1 shared paper

Studied across 14 of the same disease areas as Glucose in the shared literature.

14 shared diseases1 shared paper

Studied across 9 of the same disease areas as Glucose in the shared literature.

9 shared diseases2 shared papers

Studied across 10 of the same disease areas as Glucose in the shared literature.

10 shared diseases1 shared paper

Studied across 10 of the same disease areas as Glucose in the shared literature.

10 shared diseases1 shared paper
References & data sources
  • RxNorm (U.S. National Library of Medicine) — drug identity
  • ChEMBL (EMBL-EBI) & UniProt — pharmacology and targets
  • Europe PMC — research literature
  • ClinicalTrials.gov — clinical trials