CCL2

Gene

C-C motif chemokine ligand 2

HGNCHGNC:10618 EnsemblENSG00000108691 NCBI Gene6347

Locus: gene with protein productLocation: 17q12

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

C-C motif chemokine 2P13500

Protein · therapeutic target

Clinical-stage target · 1 candidate in clinical development

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSCYA2 · MCP1 · MCP-1 · MCAF · SMC-CF · GDCF-2 · HC11 · MGC9434

View full nomenclature history (15)

Previous symbolsSCYA2

Alias symbolsMCP1, MCP-1, MCAF, SMC-CF, GDCF-2, HC11, MGC9434

Previous namessmall inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je), chemokine (C-C motif) ligand 2

Alias namesmonocyte chemotactic protein 1, homologous to mouse Sig-je, monocyte chemoattractant protein-1, monocyte chemotactic and activating factor, monocyte secretory protein JE, small inducible cytokine subfamily A (Cys-Cys), member 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Crohn's Disease

Alcohol drinking

Inflammatory Bowel Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Chemokine ligands

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.