MKI67

Gene

marker of proliferation Ki-67

HGNCHGNC:7107 EnsemblENSG00000148773 NCBI Gene4288

Locus: gene with protein productLocation: 10q26.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Proliferation marker protein Ki-67P46013

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMIB-1 · PPP1R105 · Ki-67

View full nomenclature history (6)

Alias symbolsMIB-1, PPP1R105, Ki-67

Previous namesantigen identified by monoclonal antibody Ki-67

Alias namesprotein phosphatase 1, regulatory subunit 105, Molecular Immunology Borstel antibody 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Alcohol drinking

Urolithiasis

Intracranial Aneurysm

Smoking initiation

Intestinal Obstruction

Drug Hypersensitivity

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Protein phosphatase 1 regulatory subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.